L'oculistica e l'estrazione chirurgica dei calcoli erano le specialità dei medici preciani, facilitati dalla tradizione e dall'abilità nella lavorazione delle carni suine.
All'interno del paese sorge l'interessante chiesa parrocchiale di Santa Maria e la chiesa di Santa Caterina.

Nella parte alta del borgo si trova il quartiere Scacchi con case cinquecentesche dei medici Scacchi e Mensurati caratterizzate da decorati portali e da curiose iscrizioni con motti sugli architravi.
A borgo Preci, recente insediamento commerciale lungo la Valle Campiano, è da segnalare la chiesa della Madonna della Peschiera.
Il territorio comunale di Preci è molto suggestivo sia dal punto di vista naturalistico, poiché si estende tra la Valnerina ed il Parco Nazionale dei Monti Sibillini, sia dal punto di vista storico ed artistico, con le caratteristiche frazioni di Castelvecchio, Roccanolfi, Poggio di Croce e Montebufo.

The original fortress, built into a hillside in the second half of the thirteenth century, was devastated by an earthquake in 1328 while under the jurisdiction of Norcia. During the first half of the sixteenth century Preci was a place of refuge for exiles and was destroyed twice, once by the Papal legate to the Marches and also by Norcia. The peace treaty with Norcia was signed in 1555 and the growing success of the School of Surgery led to renewed construction in the area, giving the village its present appearance.

The urban settlement is very compact and has a sixteenth century look about it. The historical centre has numerous palaces, built between the 16th and 17th centuries by families of several doctors in Preci. The world renowned School of Surgery stems from the medical knowledge of Syrian monks who settled in the nearby Valle Castoriana. The Sant' Eutizio Abbey was equipped with an infirmary and an important library making it one of the most important centres of its kind. The doctors in Preci specialised in ophthalmology and the surgical extraction of the kidney stones, facilitated by the tradition and their skill in the processing of pork.

In the village there is the interesting parish Church of Santa Maria and the Church of Santa Caterina.The Scacchi district is found at the top end of the village with its sixteenth century houses belonging to the Scacchi and Mensurati doctors. These are notable for their decorated portals and curious inscriptions with mottos on the lintels. A commercial centre along Valle Campiano has opened recently in the village of Preci and it is worth visiting the Church of the Madonna della Peschiera.

The local municipal area set in very impressive nature, as it extends between the Valnerina and the National Park of Monti Sibillini, both from an historical and artistic point of view with the typical hamlets of Castelvecchio, Roccanolfi and Poggio di Croce Montebufo.