Worth seeing inside are frescoes and canvases by Roman painter Giovanni Miselli, 1743-1744, the Presentation in the Temple on the high altar and stucco work by Stefano Cremoni. The organ on the counter-façade, the work of Claudio Carletti da Fabriano, is very interesting. The fresco in the sacristy by Antonio Circignani is worth mentioning; it depicts The Presentation of Mary in the Temple from 1606, and has been unfortunately ruined by moisture.

Inside this church, in 1504 the friars invited the painter Pietro Vannucci, known as Perugino, to paint the entire back wall with the scene of the Adoration of the Magi, one of his greatest masterpieces. He carried out the work with such speed that he finished it the same year. It is one of the master’s greatest and most complex works. The Nativity scene he conceived and largely executed is undoubtedly one of his most beautiful works: from the splendid landscape represented in the background, to the fineness of the characters, very numerous in this composition, with thirty life-size figures and more smaller ones. The central part is the most carefully executed and shows that Perugino put all his ingenuity to work in the part that most attracts the eye of the observer, leaving the lateral groups of figures to his assistants.